Author(s):
Microbiome-inspired biomaterials are an emerging class of materials that leverage the symbiotic relationships within microbial communities to develop innovative therapeutic solutions. The human microbiome, consisting of trillions of microorganisms, plays a crucial role in maintaining health by modulating immune responses, metabolism, and tissue homeostasis. Inspired by the complex interactions within these microbial ecosystems, researchers are developing novel biomaterials that mimic or integrate microbiome-like functionality for medical applications. These biomaterials have the potential to enhance tissue regeneration, modulate immune responses, deliver drugs, and restore microbiome balance in the human body. This paper explores the principles behind microbiome-inspired biomaterials, their design strategies, and the therapeutic applications in areas such as wound healing, infection control, and personalized medicine. Challenges in translating these concepts into clinical practice, including safety concerns, scalability, and ethical considerations, are also discussed