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Bone tissue engineering (BTE) has become a crucial field in regenerative medicine, with the aim of developing effective strategies for repairing bone defects. Biomaterials play a pivotal role in this area, providing the necessary structural and biochemical support for bone regeneration. Recent innovations in injectable systems and hybrid scaffolds have shown promise in overcoming the limitations of traditional BTE approaches. Injectable biomaterials offer minimally invasive methods of delivering cells, growth factors, and scaffolds directly to the site of injury, facilitating better integration and healing. Hybrid scaffolds, which combine synthetic and natural materials, can enhance the mechanical properties, bioactivity, and biocompatibility of bone implants. This article reviews the latest advancements in injectable biomaterials and hybrid scaffolds, highlighting their potential applications, advantages, and challenges in the context of bone tissue engineering.