Author(s):
Advancements in bioelectronics and biocompatible materials have revolutionized the field of neural stimulation and brain-computer interfaces (BCIs), opening new avenues for medical therapies, neuroprosthetics, and human-computer interaction. This review explores the role of bioelectronic devices in neural modulation, highlighting the integration of biocompatible materials that ensure long-term functionality and minimize adverse tissue responses. We discuss the design principles of neural stimulators and their interface with neural tissue, focusing on key materials such as conductive polymers, metals, and hydrogels. The challenges related to device longevity, biocompatibility, and signal fidelity are also examined, along with future directions in material innovation. The review emphasizes the importance of material selection in optimizing the performance of BCIs, particularly in applications such as deep brain stimulation, sensory restoration, and cognitive enhancement. By bridging the gap between bioelectronics and biocompatibility, these advancements hold significant potential to improve the quality of life for individuals with neurological disorders and to advance human-machine interfaces
